A cost-effective o-toulidine-based Schiff base as an efficient sorbent for metal ion uptake from aqueous and soil samples: Synthesis, antimicrobial, and acute toxicity analyses

Heavy metals create serious health problems, so the practical implementation and development of low-cost sorbent materials to remove heavy from ecosystem is a worldwide issue. The purpose this study find ligand that has potential adsorb aqueous soil samples also biological potential. For this, Schiff base, dimeric o -toluidine (SBL), been synthesized through condensation, characterized by spectroscopic analysis, had its activities measured. We studied adsorption efficiency batch technique Zn(II), Co(II), Cu(II) under different conditions such as metal ion concentration, pH, contact time, SBL concentration. was analyzed Langmuir Freundlich isotherms. values correlation coefficients revealed isotherm elucidated results were more appropriable than model. Adsorption equilibrium established in 90 min for 1,440 samples. maximum all metals, optimum pH 8, it showed capacity 77 95 percent (q max ) 75.75, 62.50, 9.17 mg g -1 case Cu(II), Co(II) ions, respectively, 10.95, 64.10, 88.49 Cu (II), effectiveness sorption selected found be +2 > Zn Co antimicrobial activity investigated. moderate inhibitory against Staphylococcus dysentria , C. albican Aspergillus niger, whereas exhibited weak S. aureus, P. aureginosa, K. pneumoniae, vulgaris, E.coli when compared Fluconazole Ciprofloxacin standard. Acute toxicity compound measured daily oral administration with various doses ranging 0.1 1,000 mg/kg mice’s body weights. Even at dose mg/kg, no mortality or any type general behavioral change treated mice. Based on preparation cost, removal capacity, toxicity, activities, an excellent should pilot scale levels.